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BPC-157
Also indexed as BPC 157 · Body Protection Compound 157 · stable gastric pentadecapeptide
BPC-157 is a 15-amino-acid research peptide with a large preclinical literature concentrated in a Zagreb research group. The human evidence and product identity questions are much thinner than the online certainty suggests.
Last reviewed 2026-09-07 · education only
O que aparece na literatura
Published work discusses proposed effects across gastrointestinal, vascular and repair-related biology, but the mechanisms remain research hypotheses and the animal record does not establish a human treatment pathway.
History & development
- 1992–1993
Early PubMed-indexed work from Predrag Sikiric and colleagues described a new peptide isolated from human gastric juice and studied its protective effects in animal models.
Source: PubMed record on BPC-157 ↗
- 2011
A review in Current Pharmaceutical Design summarized the stable gastric pentadecapeptide literature and its proposed gastrointestinal biology.
Source: PubMed review ↗
- 2025
A critical review highlighted the concentration of the record in one research group and the limits on translating it to humans.
Source: 2025 literature review ↗
Approved brands & pathway
BPC-157 is presented for research-name and evidence literacy. A research name does not authenticate a product or establish a human-use pathway.
Entradas de evidência
Tema: Inflammation · arthritis · Categoria: Inflammation
BPC-157
O que a fonte sustenta
Preclinical research interest
Reviews and animal studies describe adjuvant-arthritis models and inflammatory pathways; the signal is not human arthritis evidence.
Limite: No adequate clinical evidence establishes efficacy or safety for human arthritis; BPC-157 is not approved for standard medical use.
Fonte: 2025 literature review · PubMed Ler fonte ↗
Tema: Inflammation · gastrointestinal research · Categoria: Inflammation
BPC-157
O que a fonte sustenta
Preclinical research interest
A review discusses NSAID-associated injury and rat models, including proposed nitric-oxide-related mechanisms.
Limite: Preclinical findings and review claims do not establish a human treatment pathway or dose.
Fonte: Review · PubMed Ler fonte ↗
Grade mix in this atlas
Grades describe the cited record for a narrow question. They do not score a marketplace material or make a health decision.
Naming curiosities & useful distinctions
- BPC is used in the literature for Body Protection Compound; the number 157 is part of the research name.
- “TB-500” and BPC-157 often appear together in marketplace language, but they are different research identities.
A concentrated evidence base
A long bibliography can still be concentrated in one lab. That provenance question matters when the claim jumps from animal models to human use.
Research name literacy
The BPC-157 name identifies a research subject in papers; it does not authenticate a vial, formulation, route or seller listing.
Nomes no registro
Principal research group
Predrag Sikiric and colleagues at the University of Zagreb
The public literature identifies the Zagreb group as the main source of foundational BPC-157 work; this is not a claim of sole invention.